FCGR2B Protein (C-AVI & His, Human)

Product Specifications

Abbreviation

FCGR2B

Synonyms

CD32, CD32B, FCG2, FcgammaRIIb, FCGR2, FCGR2C, FcGRIIB, FcRII-c, IGFR2

Host

HEK 293

Tag

C-AVI & His

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method

Purity

> 95 % as determined by SDS-PAGE. > 90 % as determined by SEC-HPLC

Bioactivity

Loaded Biotinylated Human FcγRIIB/C / CD32b/c protein (His & Avi Tag) (Cat. 10259-H27H-B) on SA Biosensor, can bind Bevacizumab (IgG1) with an affinity constant of 1.2 μM as determined in a BLI assay (Sartorius Octet Red384) (QC tested) .

Function

Ala46-Ile224

Molecular Weight

The recombinant mature human CD32b consists of 214 amino acids after proteolytic removal of the signal peptide and predicts a molecular mass of 24 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of the protein is approximately 35 kDa protein due to glycosylation.