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FCGR1 Protein (C-His-AVI, Rhesus)

Product Specifications

Abbreviation

FCGR1

Host

HEK 293

Tag

C-His-AVI

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method

Purity

≥ 90 % as determined by SDS-PAGE. ≥ 95 % as determined by SEC-HPLC.

Bioactivity

1.Immobilized Anti-CD20 (Research Grade Rituximab Biosimilar) at 2 μg/mL (100 μL/well) can bind Recombinant Rhesus CD64/FCGR1 Protein (His & AVI Tag), Biotinylated (Cat: 90017-K49H-B), the EC50 is 0.4-1.5 ng/mL (Routinely tested) . 2.Immobilized Anti-CTLA4 (Research grade Ipilimumab biosimilar) at 1 μg/mL (100 μL/well) can bind Recombinant Rhesus CD64/FCGR1 Protein (His & AVI Tag), Biotinylated, HPLC-verified (Cat: 90017-K49H-B), the EC50 is 0.5-2.0 ng/mL (QC tested) . 3.Recombinant Rhesus CD64/FCGR1 Protein (His & AVI Tag), Biotinylated (Cat: 90017-K49H-B) captured on Biotin CAP-Series S Sensor chip, can bind anti-ERBB2 (Research grade trastuz*mab biosimilar) with an affinity constant of 0.884 nM as determined in an SPR assay (Biacore 8K) (Routinely tested) .

Function

Met1-Pro288

Molecular Weight

The recombinant Rhesus FCGR1 consisting of 299 amino acids and has a calculated molecular mass of 33.93 kDa. As a result of glycosylation, the recombinant protein migrates as an approximately 43.4 kDa protein in SDS-PAGE under reducing conditions.

Species

Rhesus

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