FAS Protein (C-His, Rat)

Product Specifications

Abbreviation

FAS

Synonyms

Apt1, Fas, FasR, Tnfrsf6

Host

HEK 293

Tag

C-His

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method

Purity

> 90 % as determined by SDS-PAGE

Bioactivity

Measured by its ability to inhibit Fas Ligand induced apoptosis of Jurkat human acute T cell leukemia cells. The ED50 for this effect is typically 0.5-3 μg/mL in the presence of 20 ng/mL recombinant human Fas ligand.

Function

Met1-Lys170

Molecular Weight

The recombinant rat FAS comprises 160 amino acids and predicts a molecular mass of 18 kDa. As a result of glycosylation, the apparent molecular mass of the rat FAS is approximately 30-35 kDa in SDS-PAGE under reducing conditions.