FAS Protein (C-His, Human)

Product Specifications

Abbreviation

FAS

Synonyms

ALPS1A, APO-1, APT1, CD95, FAS1, FASTM, TNFRSF6

Host

HEK 293

Tag

C-His

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method

Purity

> 95 % as determined by SDS-PAGE

Bioactivity

Measured by its ability to inhibit Fas Ligand induced apoptosis of Jurkat human acute T cell leukemia cells. The ED50 for this effect is typically 0.2-1.2 μg/mL in the presence of 200ng/mL recombinant human Fas ligand.

Function

Met1-Asn173

Molecular Weight

The secreted recombinant human FAS comprises 159 amino acids and has a predicted molecular mass of 18.2 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rhFAS is approximately 35 kDa due to glycosylation.