FAS Protein (C-His, Mouse)

Product Specifications

Abbreviation

FAS

Synonyms

APO1, APT1, CD95, Fas, lpr, TNFR6, Tnfrsf6

Host

HEK 293

Tag

C-His

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method

Purity

> 98 % as determined by SDS-PAGE

Bioactivity

Measured by its ability to inhibit Fas Ligand induced apoptosis of Jurkat human acute T cell leukemia cells. The ED50 for this effect is typically 0.5-4μg/mL in the presence of 200ng/mL recombinant human Fas ligand.

Function

Met1-Arg169

Molecular Weight

The recombinant mouse FAS consists of 159 amino acids and has a predicted molecular mass of 18 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rmFAS is approximately 30-35 kDa due to glycosylation.