ERN1 Protein (N-cleavage, Human)
Product Specifications
Abbreviation
ERN1
Synonyms
HIRE1p, IRE1, IRE1a, IRE1P
Host
Baculovirus-insect Cells
Tag
N-cleavage
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method
Purity
≥ 80 % as determined by SDS-PAGE. ≥ 90 % as determined by SEC-HPLC.
Bioactivity
1. Kinase activity untested 2. Measured by its nuclease activity to cleave Xbp1 single stem-loop mini-substrate.
Function
Pro465-Leu977
Molecular Weight
The secreted recombinant human ERN1 consists of 515 amino acids and predicts a molecular mass of 58.3 KDa. The apparent molecular mass of the protein is approximately 65 KDa in SDS-PAGE under reducing conditions due to glycosylation.
Species
Human
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