ERBB3 Protein (C-mouse IgG1-Fc, Human)

Product Specifications

Abbreviation

ERBB3

Synonyms

C-erbB-3, c-erbB3, ErbB-3, erbB3-S, FERLK, HER3, LCCS2, MDA-BF-1, p180-ErbB3, p45-sErbB3, p85-sErbB3, VSCN1

Host

HEK 293

Tag

C-mouse IgG1-Fc

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method

Purity

> 95 % as determined by SDS-PAGE

Bioactivity

1.Immobilized Recombinant Human HER3 / ErbB3 Protein (Fc Tag) (Cat: 10201-H05H) at 2 μg/ml (100 μl/well) can bind biotinylated human NRG1 (Cat:11609-H01H2) (Rountinely tested) . 2.Immobilized Recombinant Human HER3 / ErbB3 Protein (Fc Tag) (Cat: 10201-H05H) at 2 μg/mL (100 μL/well) can bind Anti-Human Her3 Antibody, Human IgG1, the EC50 is 15-45 ng/mL (QC tested) .

Function

Met1-Thr643

Molecular Weight

The recombinant human ErbB3/mFc is a disulfide-linked homodimer. The reduced monomer comprises 858 amino acids and has a predicted molecular mass of 95 kDa. The apparent molecular mass of the protein is approximately 119-129 in SDS-PAGE under reducing conditions.