ERBB3 Protein (C-His-AVI, Human)
Product Specifications
Abbreviation
ERBB3
Synonyms
C-erbB-3, c-erbB3, ErbB-3, erbB3-S, FERLK, HER3, LCCS2, MDA-BF-1, p180-ErbB3, p45-sErbB3, p85-sErbB3, VSCN1
Host
HEK 293
Tag
C-His-AVI
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
Purity
> 95 % as determined by SDS-PAGE. > 95 % as determined by SEC-HPLC.
Bioactivity
1.Immobilized Recombinant Human NRG1-beta 1 Protein (ECD, Fc Tag) Cat: 11609-H01H2) at 2μg/mL (100μL/well) can bind Recombinant Human HER3/ERBB3 Protein (ECD, His & AVI Tag), Biotinylated (Cat: 10201-H49H-B), the EC50 is 75-225 ng/mL (QC tested) . 2.Immobilized Anti-HER3 (Research Grade Patritumab Biosimilar) at 2 μg/mL (100 μL/well) can bind Recombinant Human HER3/ERBB3 Protein (ECD, His & AVI Tag), Biotinylated (Cat: 10201-H49H-B), the EC50 is 0.1-0.5 ng/mL (Rountinely tested) . 3.Immobilized Recombinant Human HER3/ERBB3 Protein (ECD, His & AVI Tag), Biotinylated (Cat: 10201-H49H-B) at 1 μg/mL (100 μL/well) on streptavidin precoated (5 μg/mL, 100 μL/well) plate can bind Recombinant Human NRG1-beta 1 Protein (ECD, Fc Tag) (Cat: 11609-H01H2), the EC50 is 3-10 ng/mL (QC tested) .
Function
Met1-Thr643
Molecular Weight
The recombinant Human ERBB3 consists of 650 amino acids and predicts a molecular mass of 71.93 kDa. It migrates as an approximately 95.33 kDa band in SDS-PAGE under reducing conditions.
Species
Human
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