ERBB3 Protein (C-His, Cynomolgus, Rhesus)

Product Specifications

Abbreviation

ERBB3

Host

HEK 293

Tag

C-His

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method

Purity

> 92 % as determined by SDS-PAGE.≥ 95 % as determined by SEC-HPLC.

Bioactivity

1. Immobilized cynomolgus / rhesus ErbB3 at 2 μg/mL (100 μl/well) can bind human NRG1 (isoform Beta1), The EC50 of human NRG1 (isoform Beta1) is 0.58 μg/mL (Rountinely tested) . 2. Immobilized Anti-Human Her3 Antibody, Human IgG1 at 2 μg/mL (100 μL/well) can bind Recombinant Rhesus HER3 / ErbB3 Protein (His Tag) (Cat: 90043-K08H), the EC50 is 12-36 ng/mL (QC tested) .

Function

Met1-Thr643

Molecular Weight

The recombinant Cynomolgus / Rhesus ErbB3 consists of 635 amino acids and predicts a molecular mass of 70.1 kDa. As a result of glycosylation, cynomolgus / rhesus ErbB3 migrates as an approximately 100 kDa band in SDS-PAGE under reducing conditions.

Species

Cynomolgus, Rhesus