ERBB3 Protein (C-human IgG1-Fc, Rat)

Product Specifications

Abbreviation

ERBB3

Synonyms

Erbb3, nuc-ErbB3

Host

HEK 293

Tag

C-human IgG1-Fc

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method

Purity

> 80 % as determined by SDS-PAGE

Bioactivity

1. Immobilized rat ERBB3-Fc (Cat: 80111-R02H) at 10 μg/ml (100 μl/well) can bind biotinylated human NRG1 (isoform Beta1) (Cat: 11609-H01H2) with a linear range of 0.018-0.125 μg/ml. 2. Immobilized rat ERBB3-Fc (Cat: 80111-R02H) at 10 μg/ml (100 μl/well) can bind biotinylated human NRG1 (aa 2-246) -Fc (Cat: 11609-H04H) with a linear range of 0.018-0.25 μg/ml.

Function

Met1-His641

Molecular Weight

The recombinant rat ERBB3/Fc is a disulfide-linked homodimer. The reduced monomer comprises 863 amino acids and has a predicted molecular mass of 95.5 kDa. The apparent molecular mass of the protein is approximately 115 kDa in SDS-PAGE under reducing conditions.