ERBB3 Protein (C-His, Mouse)

Product Specifications

Abbreviation

ERBB3

Synonyms

Erbb-3, Erbb3, Erbb3r, Her3

Host

HEK 293

Tag

C-His

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method

Purity

> 93 % as determined by SDS-PAGE.≥ 90 % as determined by SEC-HPLC.

Bioactivity

1. Immobilized Recombinant Mouse HER3 / ErbB3 Protein (His Tag) (Cat:51003-M08H) at 2 μg/mL (100 μL/well) can bind Recombinant Human NRG1-beta 1 Protein (ECD, Fc Tag) (Cat:11609-H01H2), the EC50 is 3-9 ng/mL (QC tested) . 2.Immobilized Anti-HER3 (Research Grade Patritu*mab Biosimilar) at 2 μg/mL (100 μL/well) can bind Recombinant Mouse HER3 / ErbB3 Protein (His Tag) (Cat: 51003-M08H), the EC50 is 15-45 ng/mL (Rountinely tested) .

Function

Met1-His641

Molecular Weight

The secreted recombinant mouse ERBB3 comprises 633 amino acids and has a calculated molecular mass of 70 kDa. As a result of glycosylation, the apparent molecular mass of the recombinant protein is approximately 95 kDa in SDS-PAGE under reducing conditions.