ERBB2 Protein (C-human IgG1-Fc, Rhesus)

Product Specifications

Abbreviation

ERBB2

Host

HEK 293

Tag

C-human IgG1-Fc

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method

Purity

> 90 % as determined by SDS-PAGE

Bioactivity

Immobilized Her2/ERBB2 Protein, Rhesus, Recombinant (hFc Tag) (Cat:90020-K02H) at 2 μg/ml (100 μl/well) can bind Anti-Erbb2 Antibody (Trastuzumab) (Cat:68046-H002), the EC50 is 15-70 ng/mL.

Function

Met1-Thr652

Molecular Weight

The recombinant Rhesus ErbB2/Fc chimera is a disulfide-linked homodimer. The reduced monomer consists of 870 amino acids and predicts a molecular mass of 96.3 kDa. As a result of glycosylation, rhesus ErbB2/Fc monomer migrates as an approximately 130 kDa band in SDS-PAGE under reducing conditions.