ERBB2 Protein (C-His, Cynomolgus)

Product Specifications

Abbreviation

ERBB2

Host

HEK 293

Tag

C-His

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method

Purity

≥ 90 % as determined by SDS-PAGE. ≥ 90 % as determined by SEC-HPLC.

Bioactivity

1.Immobilized Her2/ERBB2 Protein, Cynomolgus, Recombinant (His Tag) (Cat:90295-C08H) at 2 μg/ml (100 μl/well) can bind Anti-HER2 (Research Grade Trastuzu*mab Biosimilar), the EC50 is 6-40 ng/mL. 2.Loaded Anti-HER2 (Research Grade Trastuzu*mab Biosimilar) on AHC Biosensor, can bind Recombinant Cynomolgus Her2/ERBB2 Protein, His Tag (Cat. No. 90295-C08H) with an affinity constant of 4.35 nM as determined in BLI assay (Sartorius Octet RED384) (Routinely tested) . 3.Immobilized Recombinant Cynomolgus HER2 / ErbB2 Protein (His Tag) (Cat: 90295-C08H) at 1 μg/mL (100 μL/well) can bind Anti-HER2 (Research Grade Pertuzu*mab Biosimilar), the EC50 is 2.2 ng/mL (Routinely tested) .

Function

Met1-Thr652

Molecular Weight

The recombinant cynomolgus ERBB2 comprises 641 amino acids and has a calculated molecular mass of 70.8 KDa. The apparent molecular mass of it is approximately 80-105 KDa in SDS-PAGE under reducing conditions due to glycosylation.

Species

Cynomolgus