EGFR Protein (C-human IgG1-Fc, Mouse)
Product Specifications
Abbreviation
EGFR
Synonyms
9030024J15Rik, Egfr, Erbb, Errb1, Errp, wa-2, wa2, Wa5
Host
HEK 293
Tag
C-human IgG1-Fc
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method
Purity
> 90 % as determined by SDS-PAGE
Bioactivity
1.Immobilized Recombinant Mouse EGFR / HER1 / ErbB1 Protein (Fc Tag) (Cat: 51091-M02H) at 2 μg/mL (100 μL/well) can bind Recombinant Human EGF/Epidermal Growth Factor Protein (Fc Tag), Biotinylated (Cat: 10605-H01H-B), the EC50 is 11.3 ng/mL (Routinely tested) . 2.Immobilized Recombinant Mouse EGFR / HER1 / ErbB1 Protein (Fc Tag) (Cat: 51091-M02H) at 2 μg/mL (100 μL/well) can bind Recombinant Mouse EGF / Epidermal Growth Factor Protein (Fc Tag), Biotinylated (Cat: 50482-M01H-B), the EC50 is 1.5-4.5 ng/mL (QC tested) .
Function
Met1-Ser647
Molecular Weight
The secreted recombinant mouse EGFR/Fc is a disulfide-linked homodimer. The reduced monomer comprises 864 amino acids and has a calculated molecular mass of 96 kDa. As a result of glycosylation, the apparent molecular mass of rmEGFR/Fc monomer is approximately 130 kDa in SDS-PAGE under reducing conditions.
Species
Mouse
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