EGFR Protein (C-human IgG1-Fc, Mouse)

Product Specifications

Abbreviation

EGFR

Synonyms

9030024J15Rik, Egfr, Erbb, Errb1, Errp, wa-2, wa2, Wa5

Host

HEK 293

Tag

C-human IgG1-Fc

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method

Purity

> 90 % as determined by SDS-PAGE

Bioactivity

1.Immobilized Recombinant Mouse EGFR / HER1 / ErbB1 Protein (Fc Tag) (Cat: 51091-M02H) at 2 μg/mL (100 μL/well) can bind Recombinant Human EGF/Epidermal Growth Factor Protein (Fc Tag), Biotinylated (Cat: 10605-H01H-B), the EC50 is 11.3 ng/mL (Routinely tested) . 2.Immobilized Recombinant Mouse EGFR / HER1 / ErbB1 Protein (Fc Tag) (Cat: 51091-M02H) at 2 μg/mL (100 μL/well) can bind Recombinant Mouse EGF / Epidermal Growth Factor Protein (Fc Tag), Biotinylated (Cat: 50482-M01H-B), the EC50 is 1.5-4.5 ng/mL (QC tested) .

Function

Met1-Ser647

Molecular Weight

The secreted recombinant mouse EGFR/Fc is a disulfide-linked homodimer. The reduced monomer comprises 864 amino acids and has a calculated molecular mass of 96 kDa. As a result of glycosylation, the apparent molecular mass of rmEGFR/Fc monomer is approximately 130 kDa in SDS-PAGE under reducing conditions.