EGFR Protein (C-mouse IgG2a-Fc, Cynomolgus)

Product Specifications

Abbreviation

EGFR

Host

HEK 293

Tag

C-mouse IgG2a-Fc

Endotoxin

< 1.0 EU per μg protein as determined by the LAL method.

Purity

≥ 95 % as determined by SDS-PAGE. ≥ 95 % as determined by SEC-HPLC.

Bioactivity

Immobilized Anti-EGFR Antibody (Cetuximab), Human IgG1 at 2 μg/mL (100 μL/well) can bind Recombinant Cynomolgus EGFR Protein (mFc Tag) (Cat: 90285-C38H), the EC50 is 10-30 ng/mL.

Function

Met1-Ser645

Molecular Weight

The recombinant Cynomolgus EGFR comprises 854 amino acids and has a predicted molecular mass of 95.06 kDa. It migrates as approximately 119.4 kDa band in SDS-PAGE under reducing conditions.