EGFR Protein (C-human IgG1-Fc, Human)
Product Specifications
Abbreviation
EGFR
Synonyms
ERBB, ERBB1, ERRP, HER1, mENA, NISBD2, PIG61
Host
Baculovirus-insect Cells
Tag
C-human IgG1-Fc
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
Purity
> 95 % as determined by SDS-PAGE.
Bioactivity
1. Immobilized EGF Protein, Human, Recombinant (ECD), HPLC-verified (Cat:10605-HNAE) at 2 μg/mL (100 μL/well) can bind EGFR Protein, Human, Recombinant (Isoform Viii, hFc Tag) (Cat:29662-H02B) in functional ELISA. 2. Immobilized Anti-EGFR (MK) -IgG1 Antibody (Cetuximab) (Cat:68069-H001) at 2 μg/mL (100 μL/well) can bind EGFR Protein, Human, Recombinant (Isoform Viii, hFc Tag) (Cat:29662-H02B), the EC50 is 4-13 ng/mL. 3. Immobilized Recombinant Human EGFR / HER1 / ErbB1 Protein (Isoform vIII, Fc Tag) (Cat: 29662-H02B) at 2 μg/mL (100 μL/well) can bind Anti-EGFR Antibody (Cetuximab), Human IgG1, the EC50 is 3.0-9.4 ng/mL (QC tested) .
Function
Met1-Lys375
Molecular Weight
The recombinant human EGFR consists of 589 amino acids and predicts a molecular mass of 65.1 kDa.
Species
Human
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