DLL1 Protein (C-human IgG1-Fc, Rat)

Product Specifications

Abbreviation

DLL1

Synonyms

Dll1

Host

HEK 293

Tag

C-human IgG1-Fc

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method

Purity

> 85 % as determined by SDS-PAGE

Bioactivity

Measured by the ability of the immobilized protein to enhance BMP2-induced alkaline phosphatase activity in C3H10T1/2 mouse embryonic fibroblast cells. The ED50 for this effect is typically 2-18 μg/mL in the presence of 500 ng/mL recombinant human BMP2.

Function

Met1-Ser534

Molecular Weight

The recombinant rat DLL1/Fc is a disulfide-linked homodimer. The reduced monomer comprises 752 amino acids and has a predicted molecular mass of 82.4 kDa. The apparent molecular mass of the protein is approximately 105.1, 57, 38.7 kDa in SDS-PAGE under reducing conditions due to glycosylation.