CXCR4 Protein (N-Flag-His & C-Strep, Human)
Product Specifications
Abbreviation
CXCR4
Synonyms
CD184, D2S201E, FB22, fusin, HM89, HSY3RR, LAP-3, LAP3, LCR1, LESTR, NPY3R, NPYR, NPYRL, NPYY3R, WHIM, WHIMS, WHIMS1
Host
HEK 293
Tag
N-Flag-His & C-Strep
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
Purity
≥ 90 % as determined by SDS-PAGE.
Bioactivity
1.Immobilized Recombinant Human CXCR4/CD184 Protein (Nanodisc, Flag-His & Strep Tag) (Cat: 11325-H95H-NA) at 5 μg/mL (100 μL/well) can bind Ulocuplumab Derived Anti-CXCR4 Antibody, Human IgG1, the EC50 is 0.5-5 ng/mL (QC tested) . 2.Anti-CXCR4 (Research Grade Ulocuplumab Biosimilar) captured on Protein A chip, can bind Recombinant Human CXCR4/CD184 Protein (Nanodisc, Flag-His & Strep Tag) (Cat: 11325-H95H-NA) with an affinity constant of 1.471 nM as determined in an SPR assay (Biacore T200) (Routinely tested) .
Function
Met1-Ser319
Molecular Weight
The recombinant Human CXCR4 comprises 357 amino acids and has a predicted molecular mass of 40.57 kDa. It migrates as approximately 48.2 kDa band in SDS-PAGE under reducing conditions.
Species
Human
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