CTSC Protein (C-His, Human)

Product Specifications

Abbreviation

CTSC

Synonyms

CPPI, DPP-I, DPP1, DPPI, HMS, JP, JPD, PALS, PDON1, PLS

Host

HEK 293

Tag

C-His

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method

Purity

> 92 % as determined by SDS-PAGE

Bioactivity

Measured by its ability to cleave the fluorogenic peptide substrate, Gly-Arg-7-amido-4-methylcoumarin (GRAMC) . The specific activity is >200 pmoles/min/μg. (Activation description: The proenzyme needs to be activated by Cathepsin L for an activated form)

Function

Met1-Leu463

Molecular Weight

The secreted recombinant human cathepsin C exists as the pro form after removal of the signal peptide. It consists of 450 amino acids and has a predicted molecular mass of 51 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rhCTSC is approximately 55 kDa.