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CTLA4 Protein (C-human IgG1-Fc, Cynomolgus, Rhesus)

Product Specifications

Abbreviation

CTLA4

Host

HEK 293

Tag

C-human IgG1-Fc

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method

Purity

> 95 % as determined by SDS-PAGE

Bioactivity

1.Immobilized human B7-1-His (Cat:10698-H08H) at 10 μg/ml (100 μl/well) can bind Cynomolgus CTLA4-Fc (Cat:90213-C02H), The EC50 of Cynomolgus CTLA4-Fc is 6.0-14.5 ng/ml (Routinely tested) . 2.Immobilized Recombinant Cynomolgus / Rhesus CTLA4 / CD152 Protein (Fc Tag) (Cat: 90213-C02H) at 5 μg/mL (100 μL/well) can bind Recombinant Cynomolgus / Rhesus CD80 / B7-1 Protein (His Tag) (Cat: 90268-C08H), the EC50 is 0.2-0.6 μg/mL (QC tested) .

Function

Met1-Asp161

Molecular Weight

The recombinant cynomolgus / rhesus CTLA4 is a disulfide-linked homodimer. The reduced monomer comprises 366 amino acids and has a calculated molecular mass of 40.4 KDa.The apparent molecular mass of the protein is approximately 52 KDa respectively in SDS-PAGE.

Species

Cynomolgus, Rhesus

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