CST7 Protein (C-His, Human)

Product Specifications

Abbreviation

CST7

Synonyms

CMAP

Host

HEK 293

Tag

C-His

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method

Purity

> 92 % as determined by SDS-PAGE

Bioactivity

Measured by its ability to inhibit active Cathepsin L cleavage of a fluorogenic peptide substrate Z-LR-AMC (R&D Systems, Catalog # ES008) . The IC50 value is <6 nM.

Function

Met1-His145

Molecular Weight

Cystatin F exists as a disulfide-linked homodimer. The human cystatin F monomer consists of 137 amino acids and and has a predicted molecular mass of 16.1 kDa. As a result of glycosylation, the recombinant Cystatin F migrates as an approximately 44 kDa band in SDS-PAGE under non-reduced conditions corresponding to the dimmer.