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CSF2RA Protein (C-human IgG1-Fc, Human)

Product Specifications

Abbreviation

CSF2RA

Synonyms

AlphaGMR, CD116, CDw116, CSF2R, CSF2RAX, CSF2RAY, CSF2RX, CSF2RY, GM-CSF-R-alpha, GMCSFR, GMCSFR-alpha, GMR, GMR-alpha, SMDP4

Host

HEK 293

Tag

C-human IgG1-Fc

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method

Purity

≥ 90 % as determined by SDS-PAGE. ≥ 95 % as determined by SEC-HPLC.

Bioactivity

1.Measured by its ability to inhibit GM-CSF dependent proliferation of TF-1 human erythroleukemic cells. The ED50 for this effect is typically 2-16 μg/ml (Routinely tested) . 2.Immobilized Recombinant Human GM-CSF / CSF2 Protein (Cat: 10015-HNAH) at 1 μg/mL (100 μL/well) can bind Recombinant Human CSF2RA / GM-CSFR / CD116 Protein (Fc Tag) (Cat: 10701-H02H), the EC50 is 5-25 ng/mL (QC tested) .

Function

Met1-Gly320

Molecular Weight

The recombinant human GM-CSFRα consists of 536 amino acids and has a predicted molecular mass of 61.2 kDa.

Species

Human

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