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CSF1R Protein (C-mouse IgG2a-Fc, Human)

Product Specifications

Abbreviation

CSF1R

Synonyms

BANDDOS, C-FMS, CD115, CSF-1R, CSFR, FIM2, FMS, GPSC, HDLS, HDLS1, M-CSF-R

Host

HEK 293

Tag

C-mouse IgG2a-Fc

Endotoxin

< 1.0 EU per μg protein as determined by the LAL method.

Purity

> 95 % as determined by SDS-PAGE.

Bioactivity

1.Measured by its ability to inhibit the human CSF-induced proliferation of M‐NFS‐60 mouse myelogenous leukemia lymphoblast cells. The ED50 for this effect is typically 0.4-1.6μg/mL in the presence of 3 ng/ml Recombinant Human M-CSF (Routinely tested) . 2.Immobilized Recombinant Human CSF1R / MCSF Receptor / CD115 Protein (Fc Tag) (Cat: 10161-H38H) at 5 μg/mL (100 μL/well) can bind Recombinant Human M-CSF / CSF-1 Protein (His Tag) (Cat: 11792-H08H), the EC50 is 4.2-12.8 ng/mL (Routinely tested) . 3.Immobilized Recombinant Human CSF1R / MCSF Receptor / CD115 Protein (Fc Tag) (Cat: 10161-H38H) at 5 μg/mL (100 μL/well) can bind Recombinant Human M-CSF/CSF1 Protein (His & AVI Tag), Biotinylated (Cat: 11792-H49H-B), the EC50 is 1-10ng/mL (QC tested) .

Function

Met1-Pro517

Molecular Weight

The recombinant human CSF1R consists of 731 amino acids and predicts a molecular mass of 81.5 kDa.

Species

Human

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