COMP Protein (C-His, Human)

Product Specifications

Abbreviation

COMP

Synonyms

CTS2, EDM1, EPD1, MED, PSACH, THBS5, TSP-5, TSP5

Host

HEK 293

Tag

C-His

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method

Purity

> 80 % as determined by SDS-PAGE

Bioactivity

Measured by its ability to induce adhesion of ATDC5 mouse chondrogenic cells.When cells are added to COMP-coated plates (0.625 μg/mL and 100 μL/well), approximately >30% cells will adhere specifically after 60 minutes at 37°C.

Function

Met1-Ala757

Molecular Weight

The mature form of human COMP consists of 748 amino acids after removal of the signal peptide and predicts a molecular mass of 82.4 kDa. As a result of glycosylation, the apparent molecular mass of rhCOMP is approximately 120-130 kDa in SDS-PAGE under reducing conditions.