CLDN6 Protein (C-His-AVI, Human)

Product Specifications

Abbreviation

CLDN6

Synonyms

UNQ757/PRO1488

Host

HEK 293

Tag

C-His-AVI

Endotoxin

< 1.0 EU per μg protein as determined by the LAL method.

Purity

≥ 75 % as determined by SDS-PAGE.

Bioactivity

1.Immobilized Recombinant Human CLDN6 -Nanodisc Protein (His & AVI Tag), Biotinylated at 5 μg/mL (100 μL/well) on streptavidin precoated (2 μg/mL) can bind Anti-Human Claudin6 Antibody, Human IgG1, the EC50 is 2-6 ng/mL. 2.Loaded Recombinant Human Claudin-6 Protein, His Tag, Biotinylated, Nanodisc (Cat: 16658-H49H-NA-B) on SA Biosensor, can bind Anti-CLDN6 antibody with an affinity constant of 1.43nM as determined in BLI assay (Sartorius Octet RED384) (Routinely tested) .

Function

Met1-Thr184

Molecular Weight

The recombinant human Claudin-6 consists of 209 amino acids and has a predicted molecular mass of 22.7 kDa. The apparent molecular mass of it is approximately 23 KDa in SDS-PAGE under reducing conditions.