CEACAM1 Protein (C-His, Human)

Product Specifications

Abbreviation

CEACAM1

Synonyms

BGP, BGP1, BGPI, CD66a

Host

HEK 293

Tag

C-His

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method

Purity

≥ 95 % as determined by SDS-PAGE ≥ 90 % as determined by SEC-HPLC.

Bioactivity

1. Measured by its ability to bind biotinylated Human CEACAM6-His (Cat:10823-H08H) in functional ELISA. 2. Measured by its ability to bind biotinylated Human CEACAM8-His (Cat:11729-H08H) in functional ELISA. 3. Measured by its ability to inhibit IL2 secretion by HuT 78 human cutaneous T cell lymphoma cells. The ED50 for this effect is typically 213 μg/mL.

Function

Met1-Gly428

Molecular Weight

The secreted recombinant human CEACAM1 comprises 405 amino acids and predicts a molecular mass of 44.8 kDa. As a result of glycosylation, the apparent molecular mass of rhCEACAM1 is approximately 60.5 kDa in SDS-PAGE under reducing conditions.