CEACAM1 Protein (C-His, Human)
Product Specifications
Abbreviation
CEACAM1
Synonyms
BGP, BGP1, BGPI, CD66a
Host
HEK 293
Tag
C-His
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method
Purity
≥ 95 % as determined by SDS-PAGE ≥ 90 % as determined by SEC-HPLC.
Bioactivity
1. Measured by its ability to bind biotinylated Human CEACAM6-His (Cat:10823-H08H) in functional ELISA. 2. Measured by its ability to bind biotinylated Human CEACAM8-His (Cat:11729-H08H) in functional ELISA. 3. Measured by its ability to inhibit IL2 secretion by HuT 78 human cutaneous T cell lymphoma cells. The ED50 for this effect is typically 213 μg/mL.
Function
Met1-Gly428
Molecular Weight
The secreted recombinant human CEACAM1 comprises 405 amino acids and predicts a molecular mass of 44.8 kDa. As a result of glycosylation, the apparent molecular mass of rhCEACAM1 is approximately 60.5 kDa in SDS-PAGE under reducing conditions.
Species
Human
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