CD93 Protein (C-His, Human)

Product Specifications

Abbreviation

CD93

Synonyms

C1qR (P), C1QR1, C1qRP, CDw93, dJ737E23.1, ECSM3, MXRA4

Host

HEK 293

Tag

C-His

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method

Purity

≥ 90 % as determined by SDS-PAGE. ≥ 90 % as determined by SEC-HPLC.

Bioactivity

1.Immobilized Human CD93 (His Tag) (Cat:12589-H08H) at 2 μg/ml (100 μl/well) can bind Human IGFBP7 (hFc Tag) (cat:13100-H02H) . The EC50 is 8-60 ng/ml (QC tested) . 2.Recombinant Human IGFBP7 / IBP-7 Protein (His Tag) (Cat: 13100-H08H) immobilized on CM5 chip, can bind Recombinant Human CD93 / C1QR1 Protein (His Tag) (Cat: 12589-H08H) with an affinity constant of 24.600 μM as determined in an SPR assay (Biacore 8K) (Routinely tested) .

Function

Met1-Lys580

Molecular Weight

The secreted recombinant human CD93 comprises 570 amino acids and has a predicted molecular mass of 59.6 kDa. As a result of glycosylation, rh CD93 migrates as an approximately 100 kDa band in SDS-PAGE under reducing conditions.