CD86 Protein (C-human IgG1-Fc, Human)
Product Specifications
Abbreviation
CD86
Synonyms
B7-2, B7.2, B70, CD28LG2, LAB72
Host
HEK 293
Tag
C-human IgG1-Fc
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
Purity
≥ 90 % as determined by SDS-PAGE. ≥ 90 % as determined by SEC-HPLC.
Bioactivity
1.Loaded Recombinant Human B7-2/CD86 Protein, hFc Tag (Cat. No. 10699-H02H) on ProA Biosensor, can bind Recombinant Human CTLA-4 Protein (Cat. No. 11159-HNAH) with an affinity constant of 5.17 nM as determined in BLI assay (Sartorius Octet RED384) (Routinely tested) . 2.Immobilized Recombinant Human CD86 / B7-2 Protein (Fc Tag) (Cat: 10699-H02H) at 5 μg/mL (100 μL/well) can bind Recombinant Human CTLA-4 Protein (ECD, Fc & AVI Tag), Biotinylated (Cat: 11159-H41H-B), the EC50 is 2-8 ng/mL (QC tested) .
Function
Met1-His239
Molecular Weight
The recombinant human CD86 consists of 458 amino acids and predicts a molecular mass of 51.9 kDa.
Species
Human
Curated Selection
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