CD86 Protein (C-human IgG1-Fc & AVI, Human)
Product Specifications
Abbreviation
CD86
Synonyms
B7-2, B7.2, B70, CD28LG2, LAB72
Host
HEK 293
Tag
C-human IgG1-Fc & AVI
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method
Purity
≥ 95 % as determined by SDS-PAGE. ≥ 95 % as determined by SEC-HPLC.
Bioactivity
1.Immobilized Recombinant Human CTLA4 / CD152 Protein (His Tag) (Cat: 11159-H08H) at 2 μg/mL (100 μl/well) can bind Recombinant Human B7-2/CD86 Protein (Fc & AVI Tag), Biotinylated (Cat: 10699-H41H-B), the EC50 is 3.5-11.0 ng/mL (QC tested) . 2.Serial dilutions of anti-CTLA4 (Research Grade Ipilimumab biosimilar) were added into Recombinant Human CTLA4 / CD152 Protein (Fc Tag) (Cat: 11159-H02H6) : Recombinant Human B7-2/CD86 Protein (Fc & AVI Tag), Biotinylated (Cat: 10699-H41H-B) binding reactions. The half maximal inhibitory concentration (IC50) is 182.7 ng/mL (Routinely tested) .
Function
Met1-His239
Molecular Weight
The recombinant Human CD86 consisting of 473 amino acids and has a calculated molecular mass of 53.7 kDa. As a result of glycosylation, the recombinant protein migrates as an approximately 92 kDa protein in SDS-PAGE under reducing conditions.
Species
Human
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