CD46 Protein (C-His, Human)

Product Specifications

Abbreviation

CD46

Synonyms

AHUS2, MCP, MGC26544, MIC10, TLX, TRA2.10

Host

HEK 293

Tag

C-His

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method

Purity

≥ 95 % as determined by SDS-PAGE. ≥ 95 % as determined by SEC-HPLC.

Bioactivity

1.Loaded YS5FL derived anti-CD46 antibody, human IgG1 on proA Biosensor, can bind Recombinant Human CD46 Protein, His Tag (Cat. No. 12239-H08H) with an affinity constant of 0.737 μM as determined in BLI assay (Sartorius Octet RED384) (Routinely tested) . 2.Immobilized Recombinant Human CD46 Protein (His Tag) (Cat: 12239-H08H) at 1 μg/mL (100 μL/well) can bind YS5FL derived Anti-CD46 antibody, the EC50 is 3.5-11.0 ng/mL (QC tested) .

Function

Met1-Asp328

Molecular Weight

The recombinant human CD46 consists of 305 amino acids and has a predicted molecular mass of 34 kDa. As a result of glycosylation, the apparent molecular mass of rh CD46 is approximately 55-60 kDa in SDS-PAGE under reducing conditions.