CD38 Protein (C-human IgG1-Fc, Human)

Product Specifications

Abbreviation

CD38

Synonyms

ADPRC 1, ADPRC1, cADPR1

Host

HEK 293

Tag

C-human IgG1-Fc

Endotoxin

< 1.0 EU per μg protein as determined by the LAL method.

Purity

≥ 95 % as determined by SDS-PAGE. ≥ 95 % as determined by SEC-HPLC.

Bioactivity

1.Measured by its ability to convert the substrate nicotinamide guanine dinucleotide (NGD+) to cyclic GDPribose.The specific activity is > 1,000 pmoles/min/μg (Routinely tested) . 2.Immobilized Recombinant Human CD38 Protein (ECD, Fc Tag) (Cat: 10818-H02H) at 2 μg/mL (100 μL/well) can bind Anti-CD38 (Research Grade Daratumu*mab Biosimilar), the EC50 is 4-15 ng/mL (QC tested) .

Function

Val43-Ile300

Molecular Weight

The recombinant human CD38 consists of 496 amino acids and predicts a molecular mass of 56.6 kDa. As a result of glycosylation, human CD38 migrates as an approximately 64.7 kDa band in SDS-PAGE under reducing conditions.