CD33 Protein (C-mouse IgG1-Fc, Human)

Product Specifications

Abbreviation

CD33

Synonyms

CD33rSiglec, FLJ00391, p67, SIGLEC-3, SIGLEC3

Host

HEK 293

Tag

C-mouse IgG1-Fc

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method

Purity

≥ 90 % as determined by SDS-PAGE. ≥ 90 % as determined by SEC-HPLC.

Bioactivity

Immobilized Recombinant Human CD33 / Siglec-3 Protein (Fc Tag) (Cat: 12238-H05H) at 2 μg/ml (100 μl/well) can bind Anti-CD33 Antibody (Lintuzumab), Human IgG1, the EC50 is 40-130 ng/mL.

Function

Met1-His259

Molecular Weight

The recombinant human CD33/mFc is a disulfide-linked homodimer. The reduced monomer comprises 476 amino acids and has a predicted molecular mass of 53.1 kDa. The apparent molecular mass of the protein is approximately 64-68 in SDS-PAGE under reducing conditions due to glycosylation.