CD276 Protein (C-human IgG1-Fc, Rat)

Product Specifications

Abbreviation

CD276

Synonyms

B7h3, B7RP-2, Cd276

Host

HEK 293

Tag

C-human IgG1-Fc

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method

Purity

> 85 % as determined by SDS-PAGE

Bioactivity

Immobilized Recombinant Rat B7-H3 / CD276 Protein (Fc Tag) (Cat: 80380-R02H) at 2 μg/mL (100 μL/well) can bind Anti-B7-H3 Antibody, IgG1 Kappa, the EC50 is 8.5-25 ng/mL.

Function

Met1-Phe244

Molecular Weight

The recombinant rat CD276/Fc is a disulfide-linked homodimer. The reduced monomer comprises 457 amino acids and has a predicted molecular mass of 50.6 kDa. The apparent molecular mass of the protein is approximately 61 kDa in SDS-PAGE under reducing conditions due to glycosylation.