CD244 Protein (C-human IgG1-Fc, Human)
Product Specifications
Abbreviation
CD244
Synonyms
2B4, NAIL, NKR2B4, Nmrk, SLAMF4
Host
HEK 293
Tag
C-human IgG1-Fc
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method
Purity
> 97 % as determined by SDS-PAGE
Bioactivity
Measured by its binding ability in a functional ELISA. Immobilized human CD48 at 10 μg/ml (100 μl/well) can bind recombinant human 2B4 / CD244 with a linear range of 0.004-0.4 μg/ml
Function
Met1-Arg221
Molecular Weight
The recombinant 2B4/CD244/Fc chimera is a disulfide-linked homodimer. The reduced monomer comprises 438 amino acids and predicts a molecular mass of 49 kDa. As a result of glycosylation, the rh2B4/CD244/Fc monomer migrates as an approximately 70-80 kDa band in SDS-PAGE under reducing conditions.
Species
Human
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