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CCR6 Protein (N-Flag-His, Human)

Product Specifications

Abbreviation

CCR6

Synonyms

BN-1, C-C CKR-6, CC-CKR-6, CCR-6, CD196, CKR-L3, CKRL3, CMKBR6, DCR2, DRY-6, DRY6, GPR-CY4, GPR29, GPRCY4, STRL22

Host

HEK 293

Tag

N-Flag-His

Endotoxin

< 1.0 EU per μg protein as determined by the LAL method.

Purity

≥ 80 % as determined by SDS-PAGE.

Bioactivity

1.Immobilized Recombinant Human CCR6 Protein (Nanodisc, Full-length, Flag-His Tag) (Cat: 11438-H88H-NA) at 5 μg/mL (100 μL/well) can bind monoclonal anti-human CCR6 antibody, human IgG1, the EC50 is 5-15 ng/mL (QC tested) . 2.Monoclonal anti-human CCR6 antibody, human IgG1 captured on CM5 chip via Anti-Human IgG Fc, can bind Recombinant Human CCR6 Protein (Nanodisc, Full-length, Flag-His Tag) (Cat: 11438-H88H-NA) with an affinity constant of 0.253 nM as determined in an SPR assay (Biacore T200) (Routinely tested) .

Function

Met1-Met374

Molecular Weight

The recombinant Human CCR6 comprises 402 amino acids and has a predicted molecular mass of 45.48 kDa. It migrates as approximately 60.6 kDa 50.7 kDa band in SDS-PAGE under reducing conditions.

Species

Human

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