BTC Protein (C-human IgG1-Fc, Rhesus)

Product Specifications

Abbreviation

BTC

Host

HEK 293

Tag

C-human IgG1-Fc

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method

Purity

> 85 % as determined by SDS-PAGE

Bioactivity

1.Measured in a cell proliferation assay using Balb/3T3 mouse embryonic fibroblast cells. The ED50 for this effect is typically 5-40 ng/mL (Routinely tested) . 2.Immobilized Recombinant Cynomolgus EGFR / HER1 / ERBB1 Protein (ECD, His Tag) (Cat: 90285-C08H) at 2 μg/mL (100 μL/well) can bind Recombinant Rhesus BTC / Betacellulin Protein (Fc Tag) (Cat: 90033-K02H), the EC50 is 50-150 ng/mL (QC tested) .

Function

Met1-Tyr111

Molecular Weight

The recombinant Rhesus BTC is a disulfide-linked homodimer. The reduced monomer comprises 321 amino acids and has a calculated molecular mass of 36 KDa.The apparent molecular mass of the protein is approximately 46 KDa respectively in SDS-PAGE.