BMPR1A Protein (C-His, Mouse)

Product Specifications

Abbreviation

BMPR1A

Synonyms

1110037I22Rik, Acvrlk3, ALK-3, ALK3, Bmpr, BMPR-1A, BMPR-IA, Bmpr1a, SKR5

Host

HEK 293

Tag

C-His

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method

Purity

> 97 % as determined by SDS-PAGE

Bioactivity

Measured by its ability to inhibit recombinant human BMP4 induced activity in MC3T3-E1 Mouse osteoblastic cells. The ED50 for this effect is typically 8-80 ng/mL in the presence of 25 ng/ml of recombinant human BMP4.

Function

Met1-Arg152

Molecular Weight

The recombinant mouse ALK3 consists of 140 amino acids after removal of the signal peptide and has a predicted molecular mass of 15.8 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rm ALK3 is approximately 30 kDa due to glycosylation.