BMPR1A Protein (C-His, Human)

Product Specifications

Abbreviation

BMPR1A

Synonyms

10q23del, ACVRLK3, ALK-3, ALK3, BMPR-1A, CD292, SKR5

Host

HEK 293

Tag

C-His

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method

Purity

> 85 % as determined by SDS-PAGE

Bioactivity

Measured by its ability to inhibit BMP4-induced alkaline phosphatase production by MC3T3E1 mouse preosteoblast cells. The ED50 for this effect is 20-120 ng/mL.

Function

Met1-Arg152

Molecular Weight

The secreted recombinant human ALK3 consists of 141 amino acids and has a predicted molecular mass of 15.7 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rhALK3 is approximately 28-33 kDa due to glycosylation.