BACE1 Protein (C-His, Human)
Product Specifications
Abbreviation
BACE1
Synonyms
ASP2, BACE, HSPC104, KIAA1149
Host
HEK 293
Tag
C-His
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method
Purity
≥ 95 % as determined by SDS-PAGE. ≥ 95 % as determined by SEC-HPLC.
Bioactivity
Measured by its ability to cleave a fluorogenic peptide substrate, Mca-SEVNLDAEFRK (Dpn) RR-NH2, R&D Systems, Catalog # ES004. The specific activity is >1.5 pmoles/min/μg.
Function
Met1-Thr457
Molecular Weight
The recombinant human BACE1 consists of 446 amino acids and has a calculated molecular mass of 49.9 kDa. As a result of glycosylation, the recombinant protein migrates as an approximately 60-65 kDa protein in SDS-PAGE under reducing conditions.
Species
Human
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