ACVRL1 Protein (C-human IgG1-Fc, Cynomolgus)

Product Specifications

Abbreviation

ACVRL1

Host

HEK 293

Tag

C-human IgG1-Fc

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method

Purity

> 90 % as determined by SDS-PAGE

Bioactivity

Measured by its ability to inhibit BMP9-induced alkaline phosphatase production by MC3T3-E1 cells. The ED50 for this effect is typically 1-5 ng/ml.

Function

Met1-Gln118

Molecular Weight

The recombinant cynomolgus ACVRL1 is a disulfide-linked homodimer. The reduced monomer comprises 338 amino acids and has a calculated molecular mass of 37.8 KDa.The apparent molecular mass of the protein is approximately 53 KDa respectively in SDS-PAGE.