ACVRL1 Protein (C-His, Human)
Product Specifications
Abbreviation
ACVRL1
Synonyms
ACVRLK1, ALK-1, ALK1, HHT, HHT2, ORW2, SKR3, TSR-I
Host
HEK 293
Tag
C-His
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method
Purity
≥ 92 % as determined by SDS-PAGE. ≥ 95 % as determined by SEC-HPLC.
Bioactivity
Measured by its ability to inhibit BMP9 induced alkaline phosphatase production by MC3T3E1 mouse chondrogenic cells The ED50 for this effect is typically 20-160 ng/mL in the presence of 2 ng/mL of recombinant human BMP9.
Function
Met1-Gln118
Molecular Weight
The recombinant human ALK1 comprises 108 amino acids and has a predicted molecular mass of 12.3 kDa. As a result of glycosylation, rhALK1 migrates as an approximately 27 kDa protein in SDS-PAGE under reducing conditions.
Species
Human
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