ACVR2B Protein (C-cleavage, Cynomolgus)

Product Specifications

Abbreviation

ACVR2B

Host

HEK 293

Tag

C-cleavage

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method

Purity

> 95 % as determined by SDS-PAGE

Bioactivity

Measured by its ability to neutralize Activin-mediated inhibition on MPC11 cell proliferation. The ED50 for this effect is typically 0.2-0.6 μg/mL in the presence of 10 ng/mL recombinant Activin A.

Function

Ser28-Thr143

Molecular Weight

The recombinant cynomolgus ACVR2B is a disulfide-linked homodimer. The reduced monomer comprises 123 amino acids and has a calculated molecular mass of 14.1 KDa.The apparent molecular mass of the protein is approximately 34 KDa in SDS-PAGE.