ACVR2B Protein (C-His, Cynomolgus)

Product Specifications

Abbreviation

ACVR2B

Host

HEK 293

Tag

C-His

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method

Purity

> 95 % as determined by SDS-PAGE

Bioactivity

Measured by its ability to neutralize Activin-mediated inhibition on MPC11 cell proliferation. The ED50 for this effect is typically 0.2-1 μg/mL in the presence of 10 ng/mL recombinant Activin A.

Function

Ser24-Thr140

Molecular Weight

The recombinant cynomolgus ACVR2B comprises 127 amino acids and has a calculated molecular mass of 14.8 KDa. The apparent molecular mass of it is approximately 33-36 KDa in SDS-PAGE under reducing conditions.