ACVR2A Protein (C-human IgG1-Fc & His, Mouse)
Product Specifications
Abbreviation
ACVR2A
Synonyms
ActrIIa, Acvr2, Acvr2a, TactrII
Host
HEK 293
Tag
C-human IgG1-Fc & His
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method
Purity
> 97 % as determined by SDS-PAGE
Bioactivity
Measured by its ability to neutralize Activin-mediated inhibition on MPC11 cell proliferation. The ED50 for this effect is typically 20-60 ng/mL in the presence of 10 ng/mL recombinant Activin A.
Function
Met1-Pro134
Molecular Weight
The secreted recombinant mouse ACVR2A/Fc chimera is a disulfide-linked homodimer. The reduced monomer comprises 363 amino acids and has a calculated molecular mass of 41.4 kDa. As a result of glycosylation, the recombinant protein migrates as an approximately 55-65 kDa band in SDS-PAGE under reducing conditions.
Species
Mouse
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