ACVR1 Protein (C-human IgG1-Fc & His, Mouse)
Product Specifications
Abbreviation
ACVR1
Synonyms
ActR-I, ActRIA, Acvr, Acvr1, Acvr1a, Acvrlk2, Alk-2, ALK2, Alk8, D330013D15Rik, SKR1, Tgfb1, Tsk7L
Host
HEK 293
Tag
C-human IgG1-Fc & His
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method
Purity
> 90 % as determined by SDS-PAGE
Bioactivity
Measure by its ability to bind with human BMP2 in a functional ELISA.
Function
Met1-Glu123
Molecular Weight
The secreted recombinant mouse ACVR1/Fc is a disulfide-linked homodimer after removal of the signal peptide. The reduced monomer comprises 351 amino acids with a predicted molecular mass of 40 kDa. As a result of glycosylation, it migrates as an approximately 45 kDa band in SDS-PAGE under reducing conditions.
Species
Mouse
Curated Selection
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