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ACVR1 Protein (C-human IgG1-Fc & His, Mouse)

Product Specifications

Abbreviation

ACVR1

Synonyms

ActR-I, ActRIA, Acvr, Acvr1, Acvr1a, Acvrlk2, Alk-2, ALK2, Alk8, D330013D15Rik, SKR1, Tgfb1, Tsk7L

Host

HEK 293

Tag

C-human IgG1-Fc & His

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method

Purity

> 90 % as determined by SDS-PAGE

Bioactivity

Measure by its ability to bind with human BMP2 in a functional ELISA.

Function

Met1-Glu123

Molecular Weight

The secreted recombinant mouse ACVR1/Fc is a disulfide-linked homodimer after removal of the signal peptide. The reduced monomer comprises 351 amino acids with a predicted molecular mass of 40 kDa. As a result of glycosylation, it migrates as an approximately 45 kDa band in SDS-PAGE under reducing conditions.

Species

Mouse

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