ACE2 Protein (C-human IgG1-Fc, Human)

1.Loaded Recombinant SARS-CoV-2 Spike RBD-mFc Recombinant Protein (HPLC-verified) (Cat. No. 40592-V05H) on AMC Biosensor, can bind Recombinant Human ACE2 / Angiotensin-Converting Enzyme 2 Protein (Fc Tag) (Cat. No. 10108-H02H-UE) with an affinity constant of 1.36 nM as determined in BLI assay (Sartorius Octet RED384) (Routinely tested) . 2.Recombinant Human ACE2 / Angiotensin-Converting Enzyme 2 Protein (Fc Tag) (Cat: 10108-H02H-UE) captured on Protein A chip, can bind Recombinant SARS-CoV-2 B.1.1.529 (Omicron) Spike S1 Protein (His Tag) (Cat: 40591-V08H41) with an affinity constant of 9.621 nM as determined in an SPR assay (Biacore T200) (Routinely tested) .

The recombinant human ACE2/Fc is a disulfide-linked homodimeric protein. The reduced monomer consists of 961 amino acids and predicts a molecular mass of 110.3 kDa. As a result of glycosylation, the band migrates approximately 140-150 kDa in the SDS-PAGE under reducing conditions.