What is the catalog number for TNFRSF1B Protein (C-His, Human)?

The catalog number for TNFRSF1B Protein (C-His, Human) is P521779.

What sizes are available for TNFRSF1B Protein (C-His, Human)?

TNFRSF1B Protein (C-His, Human) is available in the following size(s): 100 µg.

Is TNFRSF1B Protein (C-His, Human) in stock?

TNFRSF1B Protein (C-His, Human) is currently made to order / not held in immediate stock. Contact us for lead time.

TNFRSF1B Protein (C-His, Human)

Product Specifications

Abbreviation

TNFRSF1B

Synonyms

CD120b, p75, p75TNFR, TBPII, TNF-R-II, TNF-R75, TNFBR, TNFR1B, TNFR2, TNFR80

Host

HEK 293

Tag

C-His

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method

Purity

≥ 97 % as determined by SDS-PAGE. ≥ 90 % as determined by SEC-HPLC.

Bioactivity

1. Measured by its ability to inhibit TNF-α mediated cytotoxicity in L-929 mouse fibrosarcoma cells in the presence of the metabolic inhibitor actinomycin D. The ED50 for this effect is typically 0.5-5 μg/ml in the presence of 0.25 ng/mL recombinant human TNF-α. 2. Measured by its binding ability in a functional ELISA. Immobilized Human TNF-alpha (Cat:10602-HNAE) at 2 μg/ml (100 μl/well) can bind Human TNFR2/TNFRSF1B His (Cat:10417-H08H), the EC50 of Human TNFR2/TNFRSF1B His is 2.0-12.0 ng/mL.

Function

Met1-Asp257

Molecular Weight

The recombinant human TNFRII comprises 246 amino acids and has a calculated molecular mass of 26.6 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rh TNFRII is approximately 40.1 kDa due to glycosylation.