TNFRSF14 Protein (C-human IgG1-Fc & His, Mouse)

Product Specifications

Abbreviation

TNFRSF14

Synonyms

Atar, HveA, Hvem, Tnfrs14, Tnfrsf14, TR2

Host

HEK 293

Tag

C-human IgG1-Fc & His

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method

Purity

> 90 % as determined by SDS-PAGE

Bioactivity

Measured by its binding ability in a functional ELISA. Immobilized Mouse BTLA hFc (Cat:51060-M02H) at 2 μg/ml (100 μl/well) can bind Mouse HVEM Fch (Cat:10567-M03H), the EC50 of Mouse HVEM Fch is 2-10 ng/mL.

Function

Met1-Gln206

Molecular Weight

The recombinant mouse HVEM/Fc is a disulfide-linked homodimeric Protein after removal of the signal peptide. The reduced monomer consists of 415 amino acids and predicts a molecular mass of 46.4 kDa. By SDS-PAGE under reducing conditions, the apparent molecular mass of rmHVEM/Fc monomer is approximately 65 kDa due to the glycosylation.